Thalidomide does not interact with P-glycoprotein
نویسندگان
چکیده
منابع مشابه
The anthelminthic agent albendazole does not interact with p-glycoprotein.
Albendazole is a clinically important anthelminthic agent known to have variable and low oral bioavailability. The aim of this work was to determine whether albendazole, a CYP3A4 substrate, is also a substrate for the multidrug efflux transporter P-glycoprotein. Both in vitro and in vivo methods were used to assess the role of P-glycoprotein-mediated albendazole transport. In cultured LLC-PK1, ...
متن کاملShort Communication THE ANTHELMINTHIC AGENT ALBENDAZOLE DOES NOT INTERACT WITH P-GLYCOPROTEIN
Albendazole is a clinically important anthelminthic agent known to have variable and low oral bioavailability. The aim of this work was to determine whether albendazole, a CYP3A4 substrate, is also a substrate for the multidrug efflux transporter P-glycoprotein. Both in vitro and in vivo methods were used to assess the role of P-glycoprotein-mediated albendazole transport. In cultured LLCPK1, L...
متن کاملShort Communication THE ANTHELMINTHIC AGENT ALBENDAZOLE DOES NOT INTERACT WITH P-GLYCOPROTEIN
Albendazole is a clinically important anthelminthic agent known to have variable and low oral bioavailability. The aim of this work was to determine whether albendazole, a CYP3A4 substrate, is also a substrate for the multidrug efflux transporter P-glycoprotein. Both in vitro and in vivo methods were used to assess the role of P-glycoprotein-mediated albendazole transport. In cultured LLCPK1, L...
متن کاملDoes P-glycoprotein predict response to chemotherapy?
Why some cancers are curable by chemotherapy while most are not is an enigma and a major challenge for cancer researchers. The use of anticancer drugs in appropriate dosages and combinations has improved response rates and prolonged life. Yet, it is not uncommon for a patient to have a relapse during a course of chemotherapy that was initially successful. The discovery more than a decade ago th...
متن کاملDoes NP not equal P?
The paper is made rediculously irrelevant in light of realization that NP is anything a DTM can solve in time 2^p(|n|). One theorem found on one page taking up about 1 inch in exactly one text. The author therefore no longer supports the nonsense it purports.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Chemotherapy and Pharmacology
سال: 2005
ISSN: 0344-5704,1432-0843
DOI: 10.1007/s00280-005-0087-3